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Organisation of the orthobunyavirus tripodal spike and the structural changes induced by low pH and K(+) during entry

Following endocytosis, enveloped viruses employ the changing environment of maturing endosomes as cues to promote endosomal escape, a process often mediated by viral glycoproteins. We previously showed that both high [K(+)] and low pH promote entry of Bunyamwera virus (BUNV), the prototypical bunyav...

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Detalles Bibliográficos
Autores principales: Hover, Samantha, Charlton, Frank W., Hellert, Jan, Swanson, Jessica J., Mankouri, Jamel, Barr, John N., Fontana, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514341/
https://www.ncbi.nlm.nih.gov/pubmed/37735161
http://dx.doi.org/10.1038/s41467-023-41205-w