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A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years
INTRODUCTION: Maternal dietary consumption during pregnancy has been inconclusively associated with acute leukemia (AL) in infants, probably because epidemiological evidence has emerged mainly from the analysis of one-by-one nutrient, which is not a real-life scenario. Our objective was to evaluate...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514356/ https://www.ncbi.nlm.nih.gov/pubmed/37746300 http://dx.doi.org/10.3389/fonc.2023.1239147 |
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author | Mérida-Ortega, Ángel Pérez-Saldivar, María Luisa Espinoza-Hernández, Laura E. Dorantes-Acosta, Elisa M. Torres-Nava, José Refugio Solís-Labastida, Karina A. Paredes-Aguilera, Rogelio Velázquez-Aviña, Martha M. Espinosa-Elizondo, Rosa Martha Miranda-Madrazo, M. Raquel González-Ávila, Ana Itamar Rodríguez-Villalobos, Luis Rodolfo Dosta-Herrera, Juan José Mondragón-García, Javier A. Castañeda-Echevarría, Alejandro López-Caballero, M. Guadalupe Martínez-Silva, Sofía I. Rivera-González, Juan Hernández-Pineda, Norma Angélica Flores-Botello, Jesús Pérez-Gómez, Jessica Arleet Rodríguez-Vázquez, María Adriana Torres-Valle, Delfino Olvera-Durán, Jaime Ángel Martínez-Ríos, Annel García‐Cortés, Luis R. Almeida-Hernández, Carolina Flores-Lujano, Janet Núñez-Enríquez, Juan Carlos Mata-Rocha, Minerva Rosas-Vargas, Haydeé Duarte-Rodríguez, David Aldebarán Jiménez-Morales, Silvia Mejía-Arangure, Juan Manuel López-Carrillo, Lizbeth |
author_facet | Mérida-Ortega, Ángel Pérez-Saldivar, María Luisa Espinoza-Hernández, Laura E. Dorantes-Acosta, Elisa M. Torres-Nava, José Refugio Solís-Labastida, Karina A. Paredes-Aguilera, Rogelio Velázquez-Aviña, Martha M. Espinosa-Elizondo, Rosa Martha Miranda-Madrazo, M. Raquel González-Ávila, Ana Itamar Rodríguez-Villalobos, Luis Rodolfo Dosta-Herrera, Juan José Mondragón-García, Javier A. Castañeda-Echevarría, Alejandro López-Caballero, M. Guadalupe Martínez-Silva, Sofía I. Rivera-González, Juan Hernández-Pineda, Norma Angélica Flores-Botello, Jesús Pérez-Gómez, Jessica Arleet Rodríguez-Vázquez, María Adriana Torres-Valle, Delfino Olvera-Durán, Jaime Ángel Martínez-Ríos, Annel García‐Cortés, Luis R. Almeida-Hernández, Carolina Flores-Lujano, Janet Núñez-Enríquez, Juan Carlos Mata-Rocha, Minerva Rosas-Vargas, Haydeé Duarte-Rodríguez, David Aldebarán Jiménez-Morales, Silvia Mejía-Arangure, Juan Manuel López-Carrillo, Lizbeth |
author_sort | Mérida-Ortega, Ángel |
collection | PubMed |
description | INTRODUCTION: Maternal dietary consumption during pregnancy has been inconclusively associated with acute leukemia (AL) in infants, probably because epidemiological evidence has emerged mainly from the analysis of one-by-one nutrient, which is not a real-life scenario. Our objective was to evaluate the association between AL in Mexican children under 2 years of age and their mothers’ nutrients concomitant intake during pregnancy, as well as to explore whether there are differences between girls and boys. METHODS: We conducted a study of 110 cases of AL and 252 hospital-based controls in the Mexico City Metropolitan area from 2010 to 2019. We obtained information on maternal intake of 32 nutrients by a food frequency questionnaire and used weighted quantile sum regression to identify nutrient concomitant intakes. RESULTS: We found a concomitant intake of nutrients negatively associated with AL (OR 0.17; CI95% 0.03,0.88) only among girls; and we did not find a nutrient concomitant intake positively associated with AL. DISCUSSION: This is the first study that suggests nutrients that have been individually associated with AL are not necessarily the same in the presence of other nutrients (concomitant intake); as well as that maternal diet might reduce AL risk only in girls. |
format | Online Article Text |
id | pubmed-10514356 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-105143562023-09-23 A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years Mérida-Ortega, Ángel Pérez-Saldivar, María Luisa Espinoza-Hernández, Laura E. Dorantes-Acosta, Elisa M. Torres-Nava, José Refugio Solís-Labastida, Karina A. Paredes-Aguilera, Rogelio Velázquez-Aviña, Martha M. Espinosa-Elizondo, Rosa Martha Miranda-Madrazo, M. Raquel González-Ávila, Ana Itamar Rodríguez-Villalobos, Luis Rodolfo Dosta-Herrera, Juan José Mondragón-García, Javier A. Castañeda-Echevarría, Alejandro López-Caballero, M. Guadalupe Martínez-Silva, Sofía I. Rivera-González, Juan Hernández-Pineda, Norma Angélica Flores-Botello, Jesús Pérez-Gómez, Jessica Arleet Rodríguez-Vázquez, María Adriana Torres-Valle, Delfino Olvera-Durán, Jaime Ángel Martínez-Ríos, Annel García‐Cortés, Luis R. Almeida-Hernández, Carolina Flores-Lujano, Janet Núñez-Enríquez, Juan Carlos Mata-Rocha, Minerva Rosas-Vargas, Haydeé Duarte-Rodríguez, David Aldebarán Jiménez-Morales, Silvia Mejía-Arangure, Juan Manuel López-Carrillo, Lizbeth Front Oncol Oncology INTRODUCTION: Maternal dietary consumption during pregnancy has been inconclusively associated with acute leukemia (AL) in infants, probably because epidemiological evidence has emerged mainly from the analysis of one-by-one nutrient, which is not a real-life scenario. Our objective was to evaluate the association between AL in Mexican children under 2 years of age and their mothers’ nutrients concomitant intake during pregnancy, as well as to explore whether there are differences between girls and boys. METHODS: We conducted a study of 110 cases of AL and 252 hospital-based controls in the Mexico City Metropolitan area from 2010 to 2019. We obtained information on maternal intake of 32 nutrients by a food frequency questionnaire and used weighted quantile sum regression to identify nutrient concomitant intakes. RESULTS: We found a concomitant intake of nutrients negatively associated with AL (OR 0.17; CI95% 0.03,0.88) only among girls; and we did not find a nutrient concomitant intake positively associated with AL. DISCUSSION: This is the first study that suggests nutrients that have been individually associated with AL are not necessarily the same in the presence of other nutrients (concomitant intake); as well as that maternal diet might reduce AL risk only in girls. Frontiers Media S.A. 2023-09-07 /pmc/articles/PMC10514356/ /pubmed/37746300 http://dx.doi.org/10.3389/fonc.2023.1239147 Text en Copyright © 2023 Mérida-Ortega, Pérez-Saldivar, Espinoza-Hernández, Dorantes-Acosta, Torres-Nava, Solís-Labastida, Paredes-Aguilera, Velázquez-Aviña, Espinosa-Elizondo, Miranda-Madrazo, González-Ávila, Rodríguez-Villalobos, Dosta-Herrera, Mondragón-García, Castañeda-Echevarría, López-Caballero, Martínez-Silva, Rivera-González, Hernández-Pineda, Flores-Botello, Pérez-Gómez, Rodríguez-Vázquez, Torres-Valle, Olvera-Durán, Martínez-Ríos, García‐Cortés, Almeida-Hernández, Flores-Lujano, Núñez-Enríquez, Mata-Rocha, Rosas-Vargas, Duarte-Rodríguez, Jiménez-Morales, Mejía-Arangure and López-Carrillo https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Oncology Mérida-Ortega, Ángel Pérez-Saldivar, María Luisa Espinoza-Hernández, Laura E. Dorantes-Acosta, Elisa M. Torres-Nava, José Refugio Solís-Labastida, Karina A. Paredes-Aguilera, Rogelio Velázquez-Aviña, Martha M. Espinosa-Elizondo, Rosa Martha Miranda-Madrazo, M. Raquel González-Ávila, Ana Itamar Rodríguez-Villalobos, Luis Rodolfo Dosta-Herrera, Juan José Mondragón-García, Javier A. Castañeda-Echevarría, Alejandro López-Caballero, M. Guadalupe Martínez-Silva, Sofía I. Rivera-González, Juan Hernández-Pineda, Norma Angélica Flores-Botello, Jesús Pérez-Gómez, Jessica Arleet Rodríguez-Vázquez, María Adriana Torres-Valle, Delfino Olvera-Durán, Jaime Ángel Martínez-Ríos, Annel García‐Cortés, Luis R. Almeida-Hernández, Carolina Flores-Lujano, Janet Núñez-Enríquez, Juan Carlos Mata-Rocha, Minerva Rosas-Vargas, Haydeé Duarte-Rodríguez, David Aldebarán Jiménez-Morales, Silvia Mejía-Arangure, Juan Manuel López-Carrillo, Lizbeth A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years |
title | A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years |
title_full | A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years |
title_fullStr | A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years |
title_full_unstemmed | A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years |
title_short | A protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years |
title_sort | protective maternal nutrient concomitant intake associated with acute leukemia might be modified by sex, in children under 2 years |
topic | Oncology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514356/ https://www.ncbi.nlm.nih.gov/pubmed/37746300 http://dx.doi.org/10.3389/fonc.2023.1239147 |
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