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Glioblastoma cellular MAP4K1 facilitates tumor growth and disrupts T effector cell infiltration

MAP4K1 has been identified as a cancer immunotherapy target. Whether and how cancer cell-intrinsic MAP4K1 contributes to glioblastoma multiforme (GBM) progression remains unclear. We found that MAP4K1 was highly expressed in the glioma cells of human GBM specimens. High levels of MAP4K1 mRNA were pr...

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Detalles Bibliográficos
Autores principales: Sun, Jin-Min, Fan, Hong-Ye, Zhu, Yan, Pan, Ting-Ting, Wu, Yong-Ping, Zhang, Dao-Yong, Hou, Xiao-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514360/
https://www.ncbi.nlm.nih.gov/pubmed/37734869
http://dx.doi.org/10.26508/lsa.202301966

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