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Risk-stratified monitoring for thiopurine toxicity in immune-mediated inflammatory diseases: prognostic model development, validation, and, health economic evaluation

BACKGROUND: Patients established on thiopurines (e.g., azathioprine) are recommended to undergo three-monthly blood tests for the early detection of blood, liver, or kidney toxicity. These side-effects are uncommon during long-term treatment. We developed a prognostic model that could be used to inf...

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Detalles Bibliográficos
Autores principales:	Nakafero, Georgina, Card, Tim, Grainge, Matthew J., Williams, Hywel C., Taal, Maarten W., Aithal, Guruprasad P., Fox, Christopher P., Mallen, Christian D., van der Windt, Danielle A., Stevenson, Matthew D., Riley, Richard D., Abhishek, Abhishek
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514402/ https://www.ncbi.nlm.nih.gov/pubmed/37745026 http://dx.doi.org/10.1016/j.eclinm.2023.102213

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