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Efficacy of metformin targets on cardiometabolic health in the general population and non-diabetic individuals: a Mendelian randomization study

BACKGROUND: Metformin shows beneficial effects on cardiometabolic health in diabetic individuals. However, the beneficial effects in the general population, especially in non-diabetic individuals are unclear. We aim to estimate the effects of perturbation of seven metformin targets on cardiometaboli...

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Detalles Bibliográficos
Autores principales:	Zheng, Jie, Xu, Min, Yang, Qian, Hu, Chunyan, Walker, Venexia, Lu, Jieli, Wang, Jiqiu, Liu, Ruixin, Xu, Yu, Wang, Tiange, Zhao, Zhiyun, Yuan, Jinqiu, Burgess, Stephen, Au Yeung, Shiu Lun, Luo, Shan, Anderson, Emma L., Holmes, Michael V., Smith, George Davey, Ning, Guang, Wang, Weiqing, Gaunt, Tom R., Bi, Yufang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514430/ https://www.ncbi.nlm.nih.gov/pubmed/37734206 http://dx.doi.org/10.1016/j.ebiom.2023.104803

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