Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction

Glutamine:fructose-6-phosphate transaminase 1 (GFPT1) is the rate-limiting enzyme of the hexosamine biosynthetic pathway (HBP). A 54-bp exon 9 of GFPT1 is specifically included in skeletal and cardiac muscles to generate a long isoform of GFPT1 (GFPT1-L). We showed that SRSF1 and Rbfox1/2 cooperativ...

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Detalles Bibliográficos
Autores principales: Farshadyeganeh, Paniz, Nazim, Mohammad, Zhang, Ruchen, Ohkawara, Bisei, Nakajima, Kazuki, Rahman, Mohammad Alinoor, Nasrin, Farhana, Ito, Mikako, Takeda, Jun-ichi, Ohe, Kenji, Miyasaka, Yuki, Ohno, Tamio, Masuda, Akio, Ohno, Kinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514471/
https://www.ncbi.nlm.nih.gov/pubmed/37744035
http://dx.doi.org/10.1016/j.isci.2023.107746

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514471/
https://www.ncbi.nlm.nih.gov/pubmed/37744035
http://dx.doi.org/10.1016/j.isci.2023.107746

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