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Inverse-Folding Design of Yeast Telomerase RNA Increases Activity In Vitro
Saccharomyces cerevisiae telomerase RNA, TLC1, is an 1157 nt non-coding RNA that functions as both a template for DNA synthesis and a flexible scaffold for telomerase RNP holoenzyme protein subunits. The tractable budding yeast system has provided landmark discoveries about telomere biology in vivo,...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10514824/ https://www.ncbi.nlm.nih.gov/pubmed/37736897 http://dx.doi.org/10.3390/ncrna9050051 |
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