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Prospective identification of variables as outcomes for treatment (PIVOT): study protocol for a randomised, placebo-controlled trial of hydroxyurea for Ghanaian children and adults with haemoglobin SC disease

BACKGROUND: Haemoglobin SC (HbSC) is a common form of sickle cell disease (SCD), especially among individuals of West African ancestry. Persons with HbSC disease suffer from the same clinical complications and reduced quality of life that affect those with sickle cell anaemia (HbSS/Sβ(0)). Retrospec...

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Detalles Bibliográficos
Autores principales: Smart, Luke R., Segbefia, Catherine I., Latham, Teresa S., Stuber, Susan E., Amissah-Arthur, Kwesi N., Dzefi-Tettey, Klenam, Lane, Adam C., Dei-Adomakoh, Yvonne A., Ware, Russell E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515018/
https://www.ncbi.nlm.nih.gov/pubmed/37737189
http://dx.doi.org/10.1186/s13063-023-07649-7