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Astrocytes evoke a robust IRF7-independent type I interferon response upon neurotropic viral infection

BACKGROUND: Type I interferons (IFN-I) are fundamental in controlling viral infections but fatal interferonopathy is restricted in the immune-privileged central nervous system (CNS). In contrast to the well-established role of Interferon Regulatory Factor 7 (IRF7) in the regulation of IFN-I response...

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Detalles Bibliográficos
Autores principales:	Weichert, Loreen, Düsedau, Henning Peter, Fritzsch, David, Schreier, Sarah, Scharf, Annika, Grashoff, Martina, Cebulski, Kristin, Michaelsen-Preusse, Kristin, Erck, Christian, Lienenklaus, Stefan, Dunay, Ildiko Rita, Kröger, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515022/ https://www.ncbi.nlm.nih.gov/pubmed/37737190 http://dx.doi.org/10.1186/s12974-023-02892-w

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