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CD4(+)TGFβ(+) cells infiltrated the bursa of Fabricius following IBDV infection, and correlated with a delayed viral clearance, but did not correlate with disease severity, or immunosuppression

INTRODUCTION: Infectious Bursal Disease Virus (IBDV) causes immunosuppression in chickens. While B-cell destruction is the main cause of humoral immunosuppression, bursal T cells from IBDV-infected birds have been reported to inhibit the mitogenic response of splenocytes, indicating that some T cell...

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Detalles Bibliográficos
Autores principales: Nazki, Salik, Reddy, Vishwanatha R. A. P., Kamble, Nitin, Sadeyen, Jean-Remy, Iqbal, Munir, Behboudi, Shahriar, Shelton, Holly, Broadbent, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515216/
https://www.ncbi.nlm.nih.gov/pubmed/37744374
http://dx.doi.org/10.3389/fimmu.2023.1197746