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Tissue factor activates the coagulation cascade in mouse models of acute promyelocytic leukemia

Acute promyelocytic leukemia (APL) is associated with a high risk of bleeding and thrombosis. APL patients have an activated coagulation system, hyperfibrinolysis, and thrombocytopenia. APL cells express tissue factor (TF), a receptor and cofactor for factor VII/VIIa. This study had 2 goals. Firstly...

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Detalles Bibliográficos
Autores principales:	Hisada, Yohei, Kawano, Tomohiro, Archibald, Sierra J., Welch, John S., Reeves, Brandi N., Mackman, Nigel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2023
Materias:	Thrombosis and Hemostasis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515313/ https://www.ncbi.nlm.nih.gov/pubmed/37450381 http://dx.doi.org/10.1182/bloodadvances.2023010466

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