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Insight into the Binding of First- and Second-Generation PET Tracers to 4R and 3R/4R Tau Protofibrils

[Image: see text] Primary supranuclear palsy (PSP) is a rare neurodegenerative disease that perturbs body movement, eye movement, and walking balance. Similar to Alzheimer’s disease (AD), the abnormal aggregation of tau fibrils in the central neuronal and glial cells is a major hallmark of PSP disea...

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Detalles Bibliográficos
Autores principales: Li, Junhao, Kumar, Amit, Långström, Bengt, Nordberg, Agneta, Ågren, Hans
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515481/
https://www.ncbi.nlm.nih.gov/pubmed/37639522
http://dx.doi.org/10.1021/acschemneuro.3c00437