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Mechanisms of acupuncture–electroacupuncture on inflammatory pain
Acupuncture, as a traditional treatment, has been extensively used in China for thousands of years. According to the World Health Organization (WHO), acupuncture is recommended for the treatment of 77 diseases. And 16 of these diseases are related to inflammatory pain. As a combination of traditiona...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515556/ https://www.ncbi.nlm.nih.gov/pubmed/37678839 http://dx.doi.org/10.1177/17448069231202882 |
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author | Zhang, Qingxiang Zhou, Mengmeng Huo, Mingzhu Si, Yuxin Zhang, Youlin Fang, Yuxin Zhang, Di |
author_facet | Zhang, Qingxiang Zhou, Mengmeng Huo, Mingzhu Si, Yuxin Zhang, Youlin Fang, Yuxin Zhang, Di |
author_sort | Zhang, Qingxiang |
collection | PubMed |
description | Acupuncture, as a traditional treatment, has been extensively used in China for thousands of years. According to the World Health Organization (WHO), acupuncture is recommended for the treatment of 77 diseases. And 16 of these diseases are related to inflammatory pain. As a combination of traditional acupuncture and modern electrotherapy, electroacupuncture (EA) has satisfactory analgesic effects on various acute and chronic pain. Because of its good analgesic effects and no side effects, acupuncture has been widely accepted all over the world. Despite the increase in the number of studies, the mechanisms via which acupuncture exerts its analgesic effects have not been conclusively established. A literature review of related research is of great significance to elaborate on its mechanisms and to inform on further research directions. We elucidated on its mechanisms of action on inflammatory pain from two levels: peripheral and central. It includes the mechanisms of acupuncture in the periphery (immune cells and neurons, purinergic pathway, nociceptive ion channel, cannabinoid receptor and endogenous opioid peptide system) and central nervous system (TPRV1, glutamate and its receptors, glial cells, GABAergic interneurons and signaling molecules). In this review, we collected relevant recent studies to systematically explain the mechanisms of acupuncture in treating inflammatory pain, with a view to providing direction for future applications of acupuncture in inflammatory pain and promoting clinical development. |
format | Online Article Text |
id | pubmed-10515556 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-105155562023-09-23 Mechanisms of acupuncture–electroacupuncture on inflammatory pain Zhang, Qingxiang Zhou, Mengmeng Huo, Mingzhu Si, Yuxin Zhang, Youlin Fang, Yuxin Zhang, Di Mol Pain Review Acupuncture, as a traditional treatment, has been extensively used in China for thousands of years. According to the World Health Organization (WHO), acupuncture is recommended for the treatment of 77 diseases. And 16 of these diseases are related to inflammatory pain. As a combination of traditional acupuncture and modern electrotherapy, electroacupuncture (EA) has satisfactory analgesic effects on various acute and chronic pain. Because of its good analgesic effects and no side effects, acupuncture has been widely accepted all over the world. Despite the increase in the number of studies, the mechanisms via which acupuncture exerts its analgesic effects have not been conclusively established. A literature review of related research is of great significance to elaborate on its mechanisms and to inform on further research directions. We elucidated on its mechanisms of action on inflammatory pain from two levels: peripheral and central. It includes the mechanisms of acupuncture in the periphery (immune cells and neurons, purinergic pathway, nociceptive ion channel, cannabinoid receptor and endogenous opioid peptide system) and central nervous system (TPRV1, glutamate and its receptors, glial cells, GABAergic interneurons and signaling molecules). In this review, we collected relevant recent studies to systematically explain the mechanisms of acupuncture in treating inflammatory pain, with a view to providing direction for future applications of acupuncture in inflammatory pain and promoting clinical development. SAGE Publications 2023-09-20 /pmc/articles/PMC10515556/ /pubmed/37678839 http://dx.doi.org/10.1177/17448069231202882 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Review Zhang, Qingxiang Zhou, Mengmeng Huo, Mingzhu Si, Yuxin Zhang, Youlin Fang, Yuxin Zhang, Di Mechanisms of acupuncture–electroacupuncture on inflammatory pain |
title | Mechanisms of acupuncture–electroacupuncture on inflammatory pain |
title_full | Mechanisms of acupuncture–electroacupuncture on inflammatory pain |
title_fullStr | Mechanisms of acupuncture–electroacupuncture on inflammatory pain |
title_full_unstemmed | Mechanisms of acupuncture–electroacupuncture on inflammatory pain |
title_short | Mechanisms of acupuncture–electroacupuncture on inflammatory pain |
title_sort | mechanisms of acupuncture–electroacupuncture on inflammatory pain |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515556/ https://www.ncbi.nlm.nih.gov/pubmed/37678839 http://dx.doi.org/10.1177/17448069231202882 |
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