Recurrent Viral Capture of Cellular Phosphodiesterases that Antagonize OAS-RNase L

Phosphodiesterases (PDEs) encoded by viruses are putatively acquired by horizontal transfer of cellular PDE ancestor genes. Viral PDEs inhibit the OAS-RNase L antiviral pathway, a key effector component of the innate immune response. Although the function of these proteins is well-characterized, the...

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Detalles Bibliográficos
Autores principales: Goldstein, Stephen A., Elde, Nels C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515750/
https://www.ncbi.nlm.nih.gov/pubmed/37745432
http://dx.doi.org/10.1101/2023.05.12.540623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515750/
https://www.ncbi.nlm.nih.gov/pubmed/37745432
http://dx.doi.org/10.1101/2023.05.12.540623

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