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Recurrent Viral Capture of Cellular Phosphodiesterases that Antagonize OAS-RNase L
Phosphodiesterases (PDEs) encoded by viruses are putatively acquired by horizontal transfer of cellular PDE ancestor genes. Viral PDEs inhibit the OAS-RNase L antiviral pathway, a key effector component of the innate immune response. Although the function of these proteins is well-characterized, the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515750/ https://www.ncbi.nlm.nih.gov/pubmed/37745432 http://dx.doi.org/10.1101/2023.05.12.540623 |