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Lupus IgA1 autoantibodies synergize with IgG to enhance pDC responses to RNA-containing immune complexes

Autoantibodies to nuclear antigens are hallmarks of the autoimmune disease systemic lupus erythematosus (SLE) where they contribute to pathogenesis. However, there remains a gap in our knowledge regarding how different isotypes of autoantibodies contribute to disease, including the production of the...

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Detalles Bibliográficos
Autores principales: Waterman, Hayley R., Dufort, Matthew J., Posso, Sylvia E., Ni, Minjian, Li, Lucy Z., Zhu, Chengsong, Raj, Prithvi, Smith, Kelly D., Buckner, Jane H., Hamerman, Jessica A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515763/
https://www.ncbi.nlm.nih.gov/pubmed/37745328
http://dx.doi.org/10.1101/2023.09.07.556743

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