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The activation of INF2 by Piezo1/Ca(2+) is required for mesenchymal to amoeboid transition in confined environments
To invade heterogenous tissues, transformed cells may undergo a mesenchymal to amoeboid transition (MAT). However, the molecular mechanisms regulating this transition are poorly defined. In invasive melanoma cells, we demonstrate that intracellular [Ca(2+)] increases with the degree of confinement i...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cold Spring Harbor Laboratory
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515767/ https://www.ncbi.nlm.nih.gov/pubmed/37745412 http://dx.doi.org/10.1101/2023.06.23.546346 |