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Mapping the Single-cell Differentiation Landscape of Osteosarcoma

The genetic and intratumoral heterogeneity observed in human osteosarcomas (OS) poses challenges for drug development and the study of cell fate, plasticity, and differentiation, processes linked to tumor grade, cell metastasis, and survival. To pinpoint errors in OS differentiation, we transcriptio...

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Detalles Bibliográficos
Autores principales: Truong, Danh D., Weistuch, Corey, Murgas, Kevin A., Deasy, Joseph O., Mikos, Antonios G., Tannenbaum, Allen, Ludwig, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515803/
https://www.ncbi.nlm.nih.gov/pubmed/37745374
http://dx.doi.org/10.1101/2023.09.13.555156