Regulation of human interferon signaling by transposon exonization

Innate immune signaling is essential for clearing pathogens and damaged cells, and must be tightly regulated to avoid excessive inflammation or autoimmunity. Here, we found that the alternative splicing of exons derived from transposable elements is a key mechanism controlling immune signaling in hu...

Descripción completa

Detalles Bibliográficos
Autores principales: Pasquesi, Giulia Irene Maria, Allen, Holly, Ivancevic, Atma, Barbachano-Guerrero, Arturo, Joyner, Olivia, Guo, Kejun, Simpson, David M., Gapin, Keala, Horton, Isabella, Nguyen, Lily, Yang, Qing, Warren, Cody J., Florea, Liliana D., Bitler, Benjamin G., Santiago, Mario L., Sawyer, Sara L., Chuong, Edward B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515820/
https://www.ncbi.nlm.nih.gov/pubmed/37745311
http://dx.doi.org/10.1101/2023.09.11.557241

Ejemplares similares

Ejemplares similares