SOX4-SMARCA4 complex promotes glycolysis-dependent TNBC cell growth through transcriptional regulation of Hexokinase 2

Tumor cells rely on increased glycolytic capacity to promote cell growth and progression. While glycolysis is known to be upregulated in the majority of triple negative (TNBC) or basal-like subtype breast cancers, the mechanism remains unclear. Here, we used integrative genomic analyses to identify...

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Detalles Bibliográficos
Autores principales: Khanna, Pooja, Mehta, Rushabh, Mehta, Gaurav A., Bhatt, Vrushank, Guo, Jessie Y., Gatza, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515838/
https://www.ncbi.nlm.nih.gov/pubmed/37745600
http://dx.doi.org/10.1101/2023.09.10.557071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515838/
https://www.ncbi.nlm.nih.gov/pubmed/37745600
http://dx.doi.org/10.1101/2023.09.10.557071

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