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SOX4-SMARCA4 complex promotes glycolysis-dependent TNBC cell growth through transcriptional regulation of Hexokinase 2
Tumor cells rely on increased glycolytic capacity to promote cell growth and progression. While glycolysis is known to be upregulated in the majority of triple negative (TNBC) or basal-like subtype breast cancers, the mechanism remains unclear. Here, we used integrative genomic analyses to identify...
Autores principales: | Khanna, Pooja, Mehta, Rushabh, Mehta, Gaurav A., Bhatt, Vrushank, Guo, Jessie Y., Gatza, Michael L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515838/ https://www.ncbi.nlm.nih.gov/pubmed/37745600 http://dx.doi.org/10.1101/2023.09.10.557071 |
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