Broad receptor tropism and immunogenicity of a clade 3 sarbecovirus

Although Rhinolophus bats harbor diverse clade 3 sarbecoviruses, the structural determinants of receptor tropism along with the antigenicity of their spike (S) glycoproteins remain uncharacterized. Here, we show that the African Rinolophus bat clade 3 sarbecovirus PRD-0038 S has a broad ACE2 usage a...

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Detalles Bibliográficos
Autores principales: Lee, Jimin, Zepeda, Samantha K., Park, Young-Jun, Taylor, Ashley L., Quispe, Joel, Stewart, Cameron, Leaf, Elizabeth M., Treichel, Catherine, Corti, Davide, King, Neil P., Starr, Tyler N., Veesler, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515872/
https://www.ncbi.nlm.nih.gov/pubmed/37745523
http://dx.doi.org/10.1101/2023.09.12.557371

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