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Zinc is Essential for the Copper Reductase Activity of Yeast Nucleosomes

The histone H3-H4 tetramer is a copper reductase enzyme, facilitating the production of cuprous (Cu(1+)) ions for distribution to copper-dependent enzymes. It was, however, unknown if this enzymatic activity occurred within nucleosomes. To investigate this, we obtained native nucleosomes from Saccha...

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Detalles Bibliográficos
Autores principales: Vogelauer, Maria, Cheng, Chen, Karimian, Ansar, Iranpour, Hooman Golshan, Kurdistani, Siavash K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515886/
https://www.ncbi.nlm.nih.gov/pubmed/37745536
http://dx.doi.org/10.1101/2023.09.14.557765