Decoding DNA sequence-driven evolution of the human brain epigenome at cellular resolution

DNA-based evolutionary comparisons of regulatory genomic elements enable insight into functional changes, overcoming tissue inaccessibility. Here, we harnessed adult and fetal cortex single-cell ATAC-seq datasets to uncover DNA substitutions specific to the human and human-ancestral lineages within...

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Detalles Bibliográficos
Autores principales: Caglayan, Emre, Konopka, Genevieve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515917/
https://www.ncbi.nlm.nih.gov/pubmed/37745404
http://dx.doi.org/10.1101/2023.09.14.557820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515917/
https://www.ncbi.nlm.nih.gov/pubmed/37745404
http://dx.doi.org/10.1101/2023.09.14.557820

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