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Some mechanistic underpinnings of molecular adaptations of SARS-COV-2 spike protein by integrating candidate adaptive polymorphisms with protein dynamics

We integrate evolutionary predictions based on the neutral theory of molecular evolution with protein dynamics to generate mechanistic insight into the molecular adaptations of the SARS-COV-2 Spike (S) protein. With this approach, we first identified Candidate Adaptive Polymorphisms (CAPs) of the SA...

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Detalles Bibliográficos
Autores principales:	Ose, Nicholas J., Campitelli, Paul, Modi, Tushar, Can Kazan, I., Kumar, Sudhir, Banu Ozkan, S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10515954/ https://www.ncbi.nlm.nih.gov/pubmed/37745560 http://dx.doi.org/10.1101/2023.09.14.557827

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