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The TcdE holin drives toxin secretion and virulence in Clostridioides difficile

Clostridioides difficile is the leading cause of healthcare associated infections. The Pathogenicity Locus (PaLoc) toxins TcdA and TcdB promote host disease. These toxins lack canonical N-terminal signal sequences for translocation across the bacterial membrane, suggesting alternate mechanisms of re...

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Detalles Bibliográficos
Autores principales:	DiBenedetto, NV, Oberkampf, M, Cersosimo, L, Yeliseyev, V, Bry, L, Peltier, J, Dupuy, B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516005/ https://www.ncbi.nlm.nih.gov/pubmed/37745472 http://dx.doi.org/10.1101/2023.09.16.558055

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