An Overview of the Mechanisms Involved in Neuralgia

Neuralgia is a frequently occurring condition that causes chronic pain and burdens both patients and their families. Earlier research indicated that anti-inflammatory treatment, which was primarily utilized to address conditions like neuralgia, resulted in positive outcomes. However, recent years ha...

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Detalles Bibliográficos
Autores principales: Zhang, Bai-Wen, Dong, Hao, Wu, Zhe, Jiang, Xi, Zou, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516189/
https://www.ncbi.nlm.nih.gov/pubmed/37745793
http://dx.doi.org/10.2147/JIR.S425966
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author Zhang, Bai-Wen
Dong, Hao
Wu, Zhe
Jiang, Xi
Zou, Wei
author_facet Zhang, Bai-Wen
Dong, Hao
Wu, Zhe
Jiang, Xi
Zou, Wei
author_sort Zhang, Bai-Wen
collection PubMed
description Neuralgia is a frequently occurring condition that causes chronic pain and burdens both patients and their families. Earlier research indicated that anti-inflammatory treatment, which was primarily utilized to address conditions like neuralgia, resulted in positive outcomes. However, recent years have witnessed the emergence of various novel mechanisms associated with pain-related disorders. This review provides a concise overview of the inflammatory mechanisms involved in neuralgia. It also examines recent advancements in research, exploring the influence of ion channels and synaptic proteins on neuralgia and its complications. Additionally, the interactions between these mechanisms are discussed with the aim of suggesting innovative therapeutic approaches and research directions for the management of neuralgia.
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spelling pubmed-105161892023-09-23 An Overview of the Mechanisms Involved in Neuralgia Zhang, Bai-Wen Dong, Hao Wu, Zhe Jiang, Xi Zou, Wei J Inflamm Res Review Neuralgia is a frequently occurring condition that causes chronic pain and burdens both patients and their families. Earlier research indicated that anti-inflammatory treatment, which was primarily utilized to address conditions like neuralgia, resulted in positive outcomes. However, recent years have witnessed the emergence of various novel mechanisms associated with pain-related disorders. This review provides a concise overview of the inflammatory mechanisms involved in neuralgia. It also examines recent advancements in research, exploring the influence of ion channels and synaptic proteins on neuralgia and its complications. Additionally, the interactions between these mechanisms are discussed with the aim of suggesting innovative therapeutic approaches and research directions for the management of neuralgia. Dove 2023-09-18 /pmc/articles/PMC10516189/ /pubmed/37745793 http://dx.doi.org/10.2147/JIR.S425966 Text en © 2023 Zhang et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Zhang, Bai-Wen
Dong, Hao
Wu, Zhe
Jiang, Xi
Zou, Wei
An Overview of the Mechanisms Involved in Neuralgia
title An Overview of the Mechanisms Involved in Neuralgia
title_full An Overview of the Mechanisms Involved in Neuralgia
title_fullStr An Overview of the Mechanisms Involved in Neuralgia
title_full_unstemmed An Overview of the Mechanisms Involved in Neuralgia
title_short An Overview of the Mechanisms Involved in Neuralgia
title_sort overview of the mechanisms involved in neuralgia
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516189/
https://www.ncbi.nlm.nih.gov/pubmed/37745793
http://dx.doi.org/10.2147/JIR.S425966
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