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BACE1 and SCD1 are associated with neurodegeneration

INTRODUCTION: Proteolytic processing of amyloid protein precursor by β-site secretase enzyme (BACE1) is dependent on the cellular lipid composition and is affected by endomembrane trafficking in dementia and Alzheimer's disease (AD). Stearoyl-CoA desaturase 1 (SCD1) is responsible for the synth...

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Detalles Bibliográficos
Autores principales: Bedoya-Guzmán, Ferley A., Pacheco-Herrero, Mar, Salomon-Cruz, Ivan Daniel, Barrera-Sandoval, Angela Maria, Gutierrez Vargas, Johanna Andrea, Villamil-Ortiz, Javier Gustavo, Villegas Lanau, Carlos Andres, Arias-Londoño, Julián David, Area-Gomez, Estela, Cardona Gomez, Gloria Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516302/
https://www.ncbi.nlm.nih.gov/pubmed/37744400
http://dx.doi.org/10.3389/fnagi.2023.1194203