Large-scale whole exome sequencing studies identify two genes,CTSL and APOE, associated with lung cancer

Common genetic variants associated with lung cancer have been well studied in the past decade. However, only 12.3% heritability has been explained by these variants. In this study, we investigate the contribution of rare variants (RVs) (minor allele frequency <0.01) to lung cancer through two lar...

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Detalles Bibliográficos
Autores principales: Xu, Jingxiong, Xu, Wei, Choi, Jiyeon, Brhane, Yonathan, Christiani, David C., Kothari, Jui, McKay, James, Field, John K., Davies, Michael P. A., Liu, Geoffrey, Amos, Christopher I., Hung, Rayjean J., Briollais, Laurent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516417/
https://www.ncbi.nlm.nih.gov/pubmed/37738239
http://dx.doi.org/10.1371/journal.pgen.1010902

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