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CAR requires Gadd45β to promote phenobarbital-induced mouse liver tumors in early stage

Phenobarbital (PB) is an archetypal substance used as a mouse hepatocellular carcinoma (HCC) promotor in established experimental protocols. Our previous results showed CAR is the essential factor for PB induced HCC promotion. Subsequent studies suggested Gadd45β, which is induced by PB through CAR...

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Detalles Bibliográficos
Autores principales: Hori, Takeshi, Yokobori, Kosuke, Moore, Rick, Negishi, Masahiko, Sueyoshi, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516603/
https://www.ncbi.nlm.nih.gov/pubmed/37746289
http://dx.doi.org/10.3389/fonc.2023.1217847

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