Linking folding dynamics and function of SAM/SAH riboswitches at the single molecule level

Riboswitches are regulatory elements found in bacterial mRNAs that control downstream gene expression through ligand-induced conformational changes. Here, we used single-molecule FRET to map the conformational landscape of the translational SAM/SAH riboswitch and probe how co-transcriptional ligand-...

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Detalles Bibliográficos
Autores principales: Liao, Ting-Wei, Huang, Lin, Wilson, Timothy J, Ganser, Laura R, Lilley, David M J, Ha, Taekjip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516623/
https://www.ncbi.nlm.nih.gov/pubmed/37522343
http://dx.doi.org/10.1093/nar/gkad633

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