Physical interaction between MSL2 and CLAMP assures direct cooperativity and prevents competition at composite binding sites

MSL2, the DNA-binding subunit of the Drosophila dosage compensation complex, cooperates with the ubiquitous protein CLAMP to bind MSL recognition elements (MREs) on the X chromosome. We explore the nature of the cooperative binding to these GA-rich, composite sequence elements in reconstituted naïve...

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Detalles Bibliográficos
Autores principales: Eggers, Nikolas, Gkountromichos, Fotios, Krause, Silke, Campos-Sparr, Aline, Becker, Peter B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516644/
https://www.ncbi.nlm.nih.gov/pubmed/37602401
http://dx.doi.org/10.1093/nar/gkad680

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