BLM helicase protein negatively regulates stress granule formation through unwinding RNA G-quadruplex structures

Bloom's syndrome (BLM) protein is a known nuclear helicase that is able to unwind DNA secondary structures such as G-quadruplexes (G4s). However, its role in the regulation of cytoplasmic processes that involve RNA G-quadruplexes (rG4s) has not been previously studied. Here, we demonstrate that...

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Detalles Bibliográficos
Autores principales: Danino, Yehuda M, Molitor, Lena, Rosenbaum-Cohen, Tamar, Kaiser, Sebastian, Cohen, Yahel, Porat, Ziv, Marmor-Kollet, Hagai, Katina, Corine, Savidor, Alon, Rotkopf, Ron, Ben-Isaac, Eyal, Golani, Ofra, Levin, Yishai, Monchaud, David, Hickson, Ian D, Hornstein, Eran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
RNA and RNA-protein complexes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516661/
https://www.ncbi.nlm.nih.gov/pubmed/37503837
http://dx.doi.org/10.1093/nar/gkad613

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