Loss of ORP3 induces aneuploidy and promotes bladder cancer cell invasion through deregulated microtubule and actin dynamics

We have recently shown that loss of ORP3 leads to aneuploidy induction and promotes tumor formation. However, the specific mechanisms by which ORP3 contributes to ploidy-control and cancer initiation and progression is still unknown. Here, we report that ORP3 is highly expressed in ureter and bladde...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xue, Liu, Junnan, Azoitei, Anca, Eiseler, Tim, Meessen, Sabine, Jiang, Wencheng, Zheng, Xi, Makori, Arika W., Eckstein, Markus, Hartmann, Arndt, Stilgenbauer, Stephan, Elati, Mohamed, Hohwieler, Meike, Kleger, Alexander, John, Axel, Zengerling, Friedemann, Wezel, Felix, Bolenz, Christian, Günes, Cagatay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516806/
https://www.ncbi.nlm.nih.gov/pubmed/37740130
http://dx.doi.org/10.1007/s00018-023-04959-6

Ejemplares similares

Ejemplares similares