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Electric field stimulation unmasks a subtle role for T-type calcium channels in regulating lymphatic contraction

We previously identified two isoforms of T-type, voltage-gated calcium (Ca(v)3) channels (Ca(v)3.1, Ca(v)3.2) that are functionally expressed in murine lymphatic muscle cells; however, contractile tests of lymphatic vessels from single and double Ca(v)3 knock-out (DKO) mice, exhibited nearly identic...

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Detalles Bibliográficos
Autores principales: Davis, Michael J., Castorena-Gonzalez, Jorge A., Zawieja, Scott D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10516884/
https://www.ncbi.nlm.nih.gov/pubmed/37739992
http://dx.doi.org/10.1038/s41598-023-42877-6

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