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Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait

Sickle cell disease (SCD) affects millions of people worldwide. It is an autosomal recessive hemoglobinopathy that occurs due to a point mutation in the sixth codon that replaces glutamic acid with valine in the beta-globin chain. Avascular necrosis (AVN), also known as osteonecrosis, is one of its...

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Autores principales: Banait, Shashank, Banait, Tanvi, Shukla, Shivani, Mane, Supriya, Jain, Jyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517089/
https://www.ncbi.nlm.nih.gov/pubmed/37746483
http://dx.doi.org/10.7759/cureus.44006
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author Banait, Shashank
Banait, Tanvi
Shukla, Shivani
Mane, Supriya
Jain, Jyoti
author_facet Banait, Shashank
Banait, Tanvi
Shukla, Shivani
Mane, Supriya
Jain, Jyoti
author_sort Banait, Shashank
collection PubMed
description Sickle cell disease (SCD) affects millions of people worldwide. It is an autosomal recessive hemoglobinopathy that occurs due to a point mutation in the sixth codon that replaces glutamic acid with valine in the beta-globin chain. Avascular necrosis (AVN), also known as osteonecrosis, is one of its complications. In this report, we present a case of a 25-year-old female with sickle cell trait without any comorbidities who presented to us with pain in both shoulder joints for three months and was diagnosed with AVN in bilateral shoulder joints. Appropriate treatment can dramatically reduce pain and improve the quality of life for these patients. This case drew our attention due to its rare presentation.
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spelling pubmed-105170892023-09-24 Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait Banait, Shashank Banait, Tanvi Shukla, Shivani Mane, Supriya Jain, Jyoti Cureus Genetics Sickle cell disease (SCD) affects millions of people worldwide. It is an autosomal recessive hemoglobinopathy that occurs due to a point mutation in the sixth codon that replaces glutamic acid with valine in the beta-globin chain. Avascular necrosis (AVN), also known as osteonecrosis, is one of its complications. In this report, we present a case of a 25-year-old female with sickle cell trait without any comorbidities who presented to us with pain in both shoulder joints for three months and was diagnosed with AVN in bilateral shoulder joints. Appropriate treatment can dramatically reduce pain and improve the quality of life for these patients. This case drew our attention due to its rare presentation. Cureus 2023-08-23 /pmc/articles/PMC10517089/ /pubmed/37746483 http://dx.doi.org/10.7759/cureus.44006 Text en Copyright © 2023, Banait et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Genetics
Banait, Shashank
Banait, Tanvi
Shukla, Shivani
Mane, Supriya
Jain, Jyoti
Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait
title Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait
title_full Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait
title_fullStr Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait
title_full_unstemmed Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait
title_short Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait
title_sort bilateral humeral head avascular necrosis: a rare presentation in sickle cell trait
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517089/
https://www.ncbi.nlm.nih.gov/pubmed/37746483
http://dx.doi.org/10.7759/cureus.44006
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