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Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait
Sickle cell disease (SCD) affects millions of people worldwide. It is an autosomal recessive hemoglobinopathy that occurs due to a point mutation in the sixth codon that replaces glutamic acid with valine in the beta-globin chain. Avascular necrosis (AVN), also known as osteonecrosis, is one of its...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517089/ https://www.ncbi.nlm.nih.gov/pubmed/37746483 http://dx.doi.org/10.7759/cureus.44006 |
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author | Banait, Shashank Banait, Tanvi Shukla, Shivani Mane, Supriya Jain, Jyoti |
author_facet | Banait, Shashank Banait, Tanvi Shukla, Shivani Mane, Supriya Jain, Jyoti |
author_sort | Banait, Shashank |
collection | PubMed |
description | Sickle cell disease (SCD) affects millions of people worldwide. It is an autosomal recessive hemoglobinopathy that occurs due to a point mutation in the sixth codon that replaces glutamic acid with valine in the beta-globin chain. Avascular necrosis (AVN), also known as osteonecrosis, is one of its complications. In this report, we present a case of a 25-year-old female with sickle cell trait without any comorbidities who presented to us with pain in both shoulder joints for three months and was diagnosed with AVN in bilateral shoulder joints. Appropriate treatment can dramatically reduce pain and improve the quality of life for these patients. This case drew our attention due to its rare presentation. |
format | Online Article Text |
id | pubmed-10517089 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-105170892023-09-24 Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait Banait, Shashank Banait, Tanvi Shukla, Shivani Mane, Supriya Jain, Jyoti Cureus Genetics Sickle cell disease (SCD) affects millions of people worldwide. It is an autosomal recessive hemoglobinopathy that occurs due to a point mutation in the sixth codon that replaces glutamic acid with valine in the beta-globin chain. Avascular necrosis (AVN), also known as osteonecrosis, is one of its complications. In this report, we present a case of a 25-year-old female with sickle cell trait without any comorbidities who presented to us with pain in both shoulder joints for three months and was diagnosed with AVN in bilateral shoulder joints. Appropriate treatment can dramatically reduce pain and improve the quality of life for these patients. This case drew our attention due to its rare presentation. Cureus 2023-08-23 /pmc/articles/PMC10517089/ /pubmed/37746483 http://dx.doi.org/10.7759/cureus.44006 Text en Copyright © 2023, Banait et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Genetics Banait, Shashank Banait, Tanvi Shukla, Shivani Mane, Supriya Jain, Jyoti Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait |
title | Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait |
title_full | Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait |
title_fullStr | Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait |
title_full_unstemmed | Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait |
title_short | Bilateral Humeral Head Avascular Necrosis: A Rare Presentation in Sickle Cell Trait |
title_sort | bilateral humeral head avascular necrosis: a rare presentation in sickle cell trait |
topic | Genetics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517089/ https://www.ncbi.nlm.nih.gov/pubmed/37746483 http://dx.doi.org/10.7759/cureus.44006 |
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