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Methylation of BRD4 by PRMT1 regulates BRD4 phosphorylation and promotes ovarian cancer invasion

Bromodomain-containing protein 4 (BRD4), the major component of bromodomain and extra-terminal domain (BET) protein family, has important functions in early embryonic development and cancer development. However, the posttranslational modification of BRD4 is not well understood. Multiple approaches w...

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Detalles Bibliográficos
Autores principales: Liu, Yi, Liu, Hejing, Ye, Miaomiao, Jiang, Mengying, Chen, Xin, Song, Gendi, Ji, Huihui, Wang, Zhi-wei, Zhu, Xueqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517134/
https://www.ncbi.nlm.nih.gov/pubmed/37737256
http://dx.doi.org/10.1038/s41419-023-06149-5

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