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Camel nanobody-based B7-H3 CAR-T cells show high efficacy against large solid tumours

Rational design of chimeric antigen receptor T (CAR-T) cells based on the recognition of antigenic epitopes capable of evoking the most potent CAR activation is an important objective in optimizing immune therapy. In solid tumors, the B7-H3 transmembrane protein is an emerging target that harbours t...

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Detalles Bibliográficos
Autores principales:	Li, Dan, Wang, Ruixue, Liang, Tianyuzhou, Ren, Hua, Park, Chaelee, Tai, Chin-Hsien, Ni, Weiming, Zhou, Jing, Mackay, Sean, Edmondson, Elijah, Khan, Javed, Croix, Brad St, Ho, Mitchell
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517151/ https://www.ncbi.nlm.nih.gov/pubmed/37739951 http://dx.doi.org/10.1038/s41467-023-41631-w

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