Targeted demethylation of the CDO1 promoter based on CRISPR system inhibits the malignant potential of breast cancer cells

BACKGROUND: Cysteine dioxygenase 1 (CDO1) is frequently methylated, and its expression is decreased in many human cancers including breast cancer (BC). However, the functional and mechanistic aspects of CDO1 inactivation in BC are poorly understood, and the diagnostic significance of serum CDO1 meth...

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Detalles Bibliográficos
Autores principales: Yang, Jiaojiao, Sun, Liyue, Liu, Xiao‐Yun, Huang, Chan, Peng, Junling, Zeng, Xinxin, Zheng, Hailin, Cen, Wenjian, Xu, Yu‐Xia, Zhu, Weijie, Wu, Xiao‐Yan, Ling, Dongyi, Zhang, Lu‐Lu, Wei, Mingbiao, Liu, Ye, Wang, Deshen, Wang, Feng‐Hua, Li, Yu‐Hong, Li, Qin, Du, Ziming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517212/
https://www.ncbi.nlm.nih.gov/pubmed/37740473
http://dx.doi.org/10.1002/ctm2.1423

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