Dimensional clinical phenotyping using post‐mortem brain donor medical records: post‐mortem RDoC profiling is associated with Alzheimer's disease neuropathology

INTRODUCTION: Transdiagnostic dimensional phenotypes are essential to investigate the relationship between continuous symptom dimensions and pathological changes. This is a fundamental challenge to post‐mortem work, as assessments of phenotypic concepts need to rely on existing records. METHODS: We...

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Detalles Bibliográficos
Autores principales: Vogelgsang, Jonathan, Dan, Shu, Lally, Anna P., Chatigny, Michael, Vempati, Sangeetha, Abston, Joshua, Durning, Peter T., Oakley, Derek H., McCoy, Thomas H., Klengel, Torsten, Berretta, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517223/
https://www.ncbi.nlm.nih.gov/pubmed/37745891
http://dx.doi.org/10.1002/dad2.12464

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