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Ventrolateral periaqueductal gray GABAergic neurons promote arousal of sevoflurane anesthesia through cortico-midbrain circuit

The mechanism of general anesthesia remains elusive. The ventrolateral periaqueductal gray (vlPAG) in the midbrain regulates sleep and awake states. However, the role of vlPAG and its circuits in anesthesia is unclear. We utilized opto/chemogenetics, righting reflex, and electroencephalographic reco...

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Detalles Bibliográficos
Autores principales: Guo, Yongxin, Song, Yanping, Cao, Fuyang, Li, Ao, Hao, Xinyu, Shi, Wenzhu, Zhou, Zhikang, Cao, Jiangbei, Liu, Yanhong, Mi, Weidong, Tong, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517397/
https://www.ncbi.nlm.nih.gov/pubmed/37744409
http://dx.doi.org/10.1016/j.isci.2023.107486

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