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Ventrolateral periaqueductal gray GABAergic neurons promote arousal of sevoflurane anesthesia through cortico-midbrain circuit
The mechanism of general anesthesia remains elusive. The ventrolateral periaqueductal gray (vlPAG) in the midbrain regulates sleep and awake states. However, the role of vlPAG and its circuits in anesthesia is unclear. We utilized opto/chemogenetics, righting reflex, and electroencephalographic reco...
Autores principales: | Guo, Yongxin, Song, Yanping, Cao, Fuyang, Li, Ao, Hao, Xinyu, Shi, Wenzhu, Zhou, Zhikang, Cao, Jiangbei, Liu, Yanhong, Mi, Weidong, Tong, Li |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517397/ https://www.ncbi.nlm.nih.gov/pubmed/37744409 http://dx.doi.org/10.1016/j.isci.2023.107486 |
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