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PEDF inhibits LPS-induced acute lung injury in rats and promotes lung epithelial cell survival by upregulating PPAR-γ

BACKGROUND: The progression of acute lung injury (ALI) involves numerous pathological factors and complex mechanisms, and cause the destruction of epithelial and endothelial barriers. Pigment epithelium-derived factor (PEDF) is an angiogenesis inhibitor and a potential anti-inflammatory factor. The...

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Detalles Bibliográficos
Autores principales:	Xu, Lei, Chen, Yifei, Feng, Shoujie, Liu, Zeyan, Ye, Ying, Zhou, Ranran, Liu, Lijun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517507/ https://www.ncbi.nlm.nih.gov/pubmed/37740176 http://dx.doi.org/10.1186/s12890-023-02666-3

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