A novel CAR-T cell product targeting CD74 is an effective therapeutic approach in preclinical mantle cell lymphoma models

BACKGROUND: Mantle cell lymphoma (MCL) is a rare B-cell non-Hodgkin lymphoma subtype which remains incurable despite multimodal approach including chemoimmunotherapy followed by stem cell transplant, targeted approaches such as the BTK inhibitor ibrutinib, and CD19 chimeric antigen receptor (CAR) T...

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Detalles Bibliográficos
Autores principales: Chan, Wing Keung, Williams, Jessica, Sorathia, Kinnari, Pray, Betsy, Abusaleh, Kaled, Bian, Zehua, Sharma, Archisha, Hout, Ian, Nishat, Shamama, Hanel, Walter, Sloan, Shelby L., Yasin, Aneeq, Denlinger, Nathan, Zhang, Xiaoli, Muthusamy, Natarajan, Vasu, Sumithira, de Lima, Marcos, Yang, Yiping, Baiocchi, Robert, Alinari, Lapo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517521/
https://www.ncbi.nlm.nih.gov/pubmed/37740214
http://dx.doi.org/10.1186/s40164-023-00437-8

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