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Transcriptomic analysis of stem cells from chorionic villi uncovers the impact of chromosomes 2, 6 and 22 in the clinical manifestations of Down syndrome

BACKGROUND: Down syndrome (DS) clinical multisystem condition is generally considered the result of a genetic imbalance generated by the extra copy of chromosome 21. Recent discoveries, however, demonstrate that the molecular mechanisms activated in DS compared to euploid individuals are more comple...

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Detalles Bibliográficos
Autores principales:	Vaiasicca, Salvatore, Melone, Gianmarco, James, David W., Quintela, Marcos, Preziuso, Alessandra, Finnell, Richard H., Conlan, Robert Steven, Francis, Lewis W., Corradetti, Bruna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517537/ https://www.ncbi.nlm.nih.gov/pubmed/37740230 http://dx.doi.org/10.1186/s13287-023-03503-4

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