Cargando…

Deciphering pathological behavior of pediatric medullary thyroid cancer from single-cell perspective

BACKGROUND: Pediatric medullary thyroid cancer (MTC) is one of the rare pediatric endocrine neoplasms. Derived from C cells of thyroid glands, MTC is more aggressive and more prompt to metastasis than other types of pediatric thyroid cancer. The mechanism remains unclear. METHODS: We performed singl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, De-qian, Zhou, En-qing, Chen, Hui-fen, Zhan, Yong, Ye, Chun-Jing, Li, Yi, Dai, Shu-yang, Wang, Jun-feng, Chen, Lian, Dong, Kui-ran, Dong, Rui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2023
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517655/ https://www.ncbi.nlm.nih.gov/pubmed/37744240 http://dx.doi.org/10.7717/peerj.15546

Ejemplares similares

Pediatric Medullary Thyroid Carcinoma
por: Starenki, Dmytro, et al.
Publicado: (2015)

Characterization of human tear proteome reveals differentially abundance proteins in thyroid-associated ophthalmopathy
por: Zhou, Xiaoqing, et al.
Publicado: (2022)

Lactobacillus reuteri TSR332 and Lactobacillus fermentum TSF331 stabilize serum uric acid levels and prevent hyperuricemia in rats
por: Kuo, Yi-Wei, et al.
Publicado: (2021)

Pediatric Ethics Guidelines for Hereditary Medullary Thyroid Cancer
por: Rosenthal, MSara, et al.
Publicado: (2011)

Full-length transcriptome analysis of Spodoptera frugiperda larval brain reveals detoxification genes
por: Yang, Lei, et al.
Publicado: (2021)

Semaphorin4A promotes lung cancer by activation of NF-κB pathway mediated by PlexinB1
por: Wei, Xiang, et al.
Publicado: (2023)

Development and validation of prognostic nomograms for medullary thyroid cancer
por: Guan, Yong-jun, et al.
Publicado: (2019)

The polarization of microglia and infiltrated macrophages in the injured mice spinal cords: a dynamic analysis
por: Li, Jing-Lu, et al.
Publicado: (2023)

miR-455-3p ameliorates pancreatic acinar cell injury by targeting Slc2a1
por: Zhan, Yinchu, et al.
Publicado: (2023)

Early pain in females is linked to late pathological features in murine experimental osteoarthritis
por: Valdrighi, Natália, et al.
Publicado: (2023)

Embryonic exposure to fentanyl induces behavioral changes and neurotoxicity in zebrafish larvae
por: Wang, Binjie, et al.
Publicado: (2022)

Validation of low-density lipoprotein cholesterol equations in pediatric population
por: Ertürk Zararsız, Gözde, et al.
Publicado: (2023)

Novel fermented chickpea milk with enhanced level of γ-aminobutyric acid and neuroprotective effect on PC12 cells
por: Li, Wen, et al.
Publicado: (2016)

Therapeutic role of human hepatocyte growth factor (HGF) in treating hair loss
por: Qi, Yonghao, et al.
Publicado: (2016)

The effect of cartilage decellularized extracellular matrix-chitosan compound on treating knee osteoarthritis in rats
por: Chen, Deng, et al.
Publicado: (2021)

Advanced oxidation protein products induce annulus fibrosus cell senescence through a NOX4-dependent, MAPK-mediated pathway and accelerate intervertebral disc degeneration
por: Dai, Xiangheng, et al.
Publicado: (2022)

Isopsoralen suppresses receptor activator of nuclear factor kappa-β ligand-induced osteoclastogenesis by inhibiting the NF-κB signaling
por: Zhan, Wanda, et al.
Publicado: (2023)

A new miniMOS tool kit capable of visualizing single copy insertion in C. elegans
por: Li, Jiangyun, et al.
Publicado: (2023)

Pathological mechanism of heart failure with preserved ejection fraction in rats based on iTRAQ technology
por: Xu, Hang, et al.
Publicado: (2023)

Functions of 1,25-dihydroxy vitamin D3, vitamin D3 receptor and interleukin-22 involved in pathogenesis of gout arthritis through altering metabolic pattern and inflammatory responses
por: Chen, Yuqi, et al.
Publicado: (2021)

Analyses of antioxidant status and nucleotide alterations in genes encoding antioxidant enzymes in patients with benign and malignant thyroid disorders
por: Ramli, Nur Siti Fatimah, et al.
Publicado: (2017)

Evaluation of structural and ultrastructural changes in thyroid and parathyroid glands after near infrared irradiation: study on an animal model
por: Serra, Carlos, et al.
Publicado: (2021)

Identification and validation of hub genes for diabetic retinopathy
por: Peng, Li, et al.
Publicado: (2021)

Pathological characteristics and genetic features of melanin-producing medullary thyroid carcinoma
por: Wang, Changsong, et al.
Publicado: (2018)

Thyroid: Medullary Carcinoma
por: Somnay, Yash R., et al.
Publicado: (2013)

Tissue and serum samples of patients with papillary thyroid cancer with and without benign background demonstrate different altered expression of proteins
por: Abdullah, Mardiaty Iryani, et al.
Publicado: (2016)

Activity of roniciclib in medullary thyroid cancer
por: Lin, Shu-Fu, et al.
Publicado: (2018)

The Cellular and Molecular Landscape of Synchronous Pediatric Sialoblastoma and Hepatoblastoma
por: Yang, Ran, et al.
Publicado: (2022)

High-level expression and molecular characterization of a recombinant prolidase from Escherichia coli NovaBlue
por: Wang, Tzu-Fan, et al.
Publicado: (2018)

Identification of hub genes and small molecule therapeutic drugs related to breast cancer with comprehensive bioinformatics analysis
por: Hao, Mingqian, et al.
Publicado: (2020)

Patterns of thyroid hormone levels in pediatric medullary thyroid carcinoma patients on vandetanib therapy
por: Lodish, Maya, et al.
Publicado: (2015)

Testosterone Retention Mechanism in Sertoli Cells: A Biochemical Perspective
por: Gill-Sharma, Manjeet Kaur
Publicado: (2018)

Fungal survival under temperature stress: a proteomic perspective
por: Abu Bakar, Nurlizah, et al.
Publicado: (2020)

Genome-wide characterization and expression analysis of bHLH gene family in physic nut (Jatropha curcas L.)
por: Zhang, Lin, et al.
Publicado: (2022)

Recombinant fusion protein by lysozyme and antibacterial peptide enhances ischemic wound healing via angiogenesis and reduction of inflammation in diabetic db/db mice
por: Li, Wei, et al.
Publicado: (2021)

Metabolomics of a cell line-derived xenograft model reveals circulating metabolic signatures for malignant mesothelioma
por: Gao, Yun, et al.
Publicado: (2022)

Comparison of pediatric and adult medullary thyroid carcinoma based on SEER program
por: Zhao, Zhuang, et al.
Publicado: (2020)

Novel epitopes identified from efflux pumps of Mycobacterium tuberculosis could induce cytotoxic T lymphocyte response
por: Zhai, Ming-xia, et al.
Publicado: (2015)

Construction of fibronectin conditional gene knock-out mice and the effect of fibronectin gene knockout on hematopoietic, biochemical and immune parameters in mice
por: Yuan, Xiaohong, et al.
Publicado: (2020)

Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes
por: Lasagna-Reeves, Cristian A, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_sbtpd6llcsadqq1q284e03m5tc