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Modelling and analysis of the complement system signalling pathways: roles of C3, C5a and pro-inflammatory cytokines in SARS-CoV-2 infection

The complement system is an essential part of innate immunity. It is activated by invading pathogens causing inflammation, opsonization, and lysis via complement anaphylatoxins, complement opsonin’s and membrane attack complex (MAC), respectively. However, in SARS-CoV-2 infection overactivation of c...

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Detalles Bibliográficos
Autores principales:	Murad, Didar, Zafar Paracha, Rehan, Saeed, Muhammad Tariq, Ahmad, Jamil, Mushtaq, Ammar, Humayun, Maleeha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2023
Materias:	Bioinformatics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517668/ https://www.ncbi.nlm.nih.gov/pubmed/37744234 http://dx.doi.org/10.7717/peerj.15794

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