NOXA expression is downregulated in human breast cancer undergoing incomplete pathological response and senescence after neoadjuvant chemotherapy

Neoadjuvant chemotherapy (NAC) is a frequently utilized approach to treat locally advanced breast cancer, but, unfortunately, a subset of tumors fails to undergo complete pathological response. Apoptosis and therapy-induced senescence (TIS) are both cell stress mechanisms but their exact role in med...

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Detalles Bibliográficos
Autores principales: Al Shboul, Sofian, El-Sadoni, Mohammed, Alhesa, Ahmad, Abu Shahin, Nisreen, Abuquteish, Dua, Abu Al Karsaneh, Ola, Alsharaiah, Elham, Ismail, Mohammad A., Tyutyunyk-Massey, Liliya, Alotaibi, Moureq R., Neely, Victoria, Harada, Hisashi, Saleh, Tareq
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10517932/
https://www.ncbi.nlm.nih.gov/pubmed/37741850
http://dx.doi.org/10.1038/s41598-023-42994-2

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