A novel SLC25A1 inhibitor, parthenolide, suppresses the growth and stemness of liver cancer stem cells with metabolic vulnerability

Liver cancer stem cells (LCSCs) are recognized as key contributors to hepatocarcinogenesis, progression, and recurrence. Consequently, eradicating LCSCs has a great chance of increasing long-term survival in patients with liver cancer. Parthenolide (PTL), a natural sesquiterpene lactone product, pos...

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Detalles Bibliográficos
Autores principales: Zhang, Zhichun, Qiao, Yuan, Sun, Qiuyue, Peng, Liang, Sun, Lichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518014/
https://www.ncbi.nlm.nih.gov/pubmed/37741815
http://dx.doi.org/10.1038/s41420-023-01640-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518014/
https://www.ncbi.nlm.nih.gov/pubmed/37741815
http://dx.doi.org/10.1038/s41420-023-01640-6

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