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A novel SLC25A1 inhibitor, parthenolide, suppresses the growth and stemness of liver cancer stem cells with metabolic vulnerability
Liver cancer stem cells (LCSCs) are recognized as key contributors to hepatocarcinogenesis, progression, and recurrence. Consequently, eradicating LCSCs has a great chance of increasing long-term survival in patients with liver cancer. Parthenolide (PTL), a natural sesquiterpene lactone product, pos...
Autores principales: | Zhang, Zhichun, Qiao, Yuan, Sun, Qiuyue, Peng, Liang, Sun, Lichao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518014/ https://www.ncbi.nlm.nih.gov/pubmed/37741815 http://dx.doi.org/10.1038/s41420-023-01640-6 |
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