Alpha synuclein modulates mitochondrial Ca(2+) uptake from ER during cell stimulation and under stress conditions

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Alpha synuclein (a-syn) is an intrinsically disordered protein prevalent in neurons, and aggregated forms are associated with synucleinopathies including Parkinson’s disease (PD). Despite the biomedical importance and extensive studies, the physiological role of a-syn and its participation in etiolo...

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Detalles Bibliográficos
Autores principales: Ramezani, Meraj, Wagenknecht-Wiesner, Alice, Wang, Tong, Holowka, David A., Eliezer, David, Baird, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10518018/
https://www.ncbi.nlm.nih.gov/pubmed/37741841
http://dx.doi.org/10.1038/s41531-023-00578-x
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